Microfluidic technology

Advances in microfluidics technology are revolutionizing molecular biology procedures for enzymatic analysis (e.g., glucose and lactate assays), DNA analysis (e.g., polymerase chain reaction and high-throughput sequencing), and proteomics. The basic idea of microfluidic biochips is to integrate assay operations such as . PDMS bloc for microfluidic device manufacturing PDMS Block. The polymer most commonly used for molding microfluidic . It is the science and technology of systems that process or manipulate small (10–to 10–litres) amounts of fluids, using channels with dimensions of tens to hundreds of micrometres.

The first applications of microfluidic technologies have been in analy- sis, for which they offer a .

Author information: (1) Clearbridge BioMedics Pte Lt Singapore, Singapore.

Presence of circulating tumor cells (CTCs) in blood is an important intermediate step in cancer metastasis, a mortal consequence of cancer. However, CTCs are extremely rare in blood with highly . Some examples of systems and processes that might employ this technology include inkjet printers, blood-cell-separation equipment, biochemical assays, chemical synthesis, genetic analysis, drug screening, electrochromatography, surface . Microfluidic systems have diverse and widespread potential applications. In this review, we first discuss the formation mechanism of nanoparticles prepared by microfluidic mixing. This Account aims to inform the nanomaterials community about how microfluidic technologies can supplement flask experimentation for the ensemble investigation of formation mechanisms and design of semiconductor nanocrystals . We present selected studies outlining the preparation of quantum dots . Dolomite Bio systems employ the principle of microfluidic flow technology focussing to encapsulate single cells in millions of aqueous droplets in oil.

Lignos I(1), Maceiczyk R(1), deMello AJ(1). Branchford BR(1), Ng CJ(1), Neeves KB(2), Di Paola J(3). Molecular diagnostics have helped to improve the lives of . Our technology makes it possible to screen millions of individual cells (or up to one billion in pools). Check out our equipment today to achieve superior processing solutions! The fundamental principles, generation and manipulation of droplet-based microfluidic technology were . AN OVERVIEW OF MICROFLUIDIC TECHNOLOGIES.

D spherical microtissues and microfluidic technology for multi- tissue experiments and analysis. Kim JY(1), Fluri DA(2), Marchan R(3), Boonen K (4), Mohanty S(1), Singh P(1), Hammad S(5), Landuyt B(4), Hengstler JG(3), Kelm . Huang Y(1), Williams JC, Johnson SM. Protein crystallization using microfluidic technologies based on valves, droplets, and SlipChip. Building on its origins in semiconductor technology and chemical separations, . Fluid flow in ultralow dimensions of micrometers is laminar and can be precisely controlled by adjusting the flow rate. The distinct property gives rise to . Many technologies for manipulating sperm have been developed over the past few decades and these have focused on counting and sorting sperm.

Microfludic technologies were introduced into this field at the beginning of the st . The microenvironment has to mimic in vivo physiological conditions including spatial and temporal dimensions and dynamics, physical interactions, and biochemical settings. This book describes the most important and state-of-the-art microfluidic technologies and the underlying principles utilized in the implementation of fluidic protocols of .